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21c Museum Hotel Lexington

4.4(1,399)
Hotel

About

21c Museum Hotel Lexington offers a blend of contemporary art and boutique comfort in downtown Lexington's historic Fayette National Bank building. Its thoughtfully designed rooms feature spacious layouts, Nespresso machines, and work-friendly tables, making it ideal for productive stays and small meetings.

The hotel provides private event spaces infused with cultural flair, perfect for corporate gatherings and receptions. Located on Main Street, it offers easy access to local business hubs and attractions like Keeneland Race Course and the Kentucky Bourbon Trail, with valet parking and in-room dining enhancing convenience.

Best for

  • Boutique downtown hotel stays with artful ambiance
  • Private events & corporate receptions
  • In-room dining & focused work sessions

Request a Package

Tell the venue what you're planning and they'll respond with a custom proposal within 1–2 business days.

Group Meeting

Custom request

Professional meeting space for your team — whether it's a meeting, training, workshop, or multi-day offsite. Half-day, full-day, or multi-day — with the option to request AV, catering, and your preferred room layout.

What's typically included

  • Meeting room & layout
  • Food & beverage
  • AV & technology

Room Block

Custom request

Reserve a block of rooms for your group — ideal for multi-day conferences, offsites, or any event where attendees are traveling from out of town.

What's typically included

  • Reserved guest rooms for your group
  • Flexible check-in & check-out dates
  • Negotiated group rates

Meeting + Room Block

Custom request

Bundle your meeting space and guest rooms in one request — perfect for multi-day offsites and conferences where the team meets by day and stays overnight.

What's typically included

  • Meeting room & layout
  • Food & beverage
  • AV & technology
  • Reserved guest rooms for your group

Venue Details

Standout features

Architecture & Art
Museum hotel in a historic 1914 bank building
The hotel transforms the former Fayette National Bank into a contemporary art-filled space with immersive installations like the Nightwatch Artist Suite and the Spectralline entry by SOFTLab, blending history with modern design.
Location
Downtown Lexington on Main Street
Centrally located in the heart of Lexington, the hotel offers easy access to local attractions like Keeneland Race Course and the Kentucky Bourbon Trail, making it convenient for business travelers and event guests.
In-Room Amenities
Well-appointed rooms with workspace and Nespresso bar
Rooms feature comfortable beds, spacious layouts with sofas, dedicated work tables, and in-room coffee bars equipped with Nespresso machines, supporting both relaxation and productivity.

At a glance

Rated 4.4 on Google · 1,399 reviews