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21c Museum Hotel St Louis

4.1(929)
Hotel

About

21c Museum Hotel St Louis blends contemporary art with hospitality in a beautifully restored downtown building. Its rotating gallery exhibitions and playful installations create a dynamic backdrop for meetings and events, offering a creative edge few city hotels match.

The hotel features spacious, modern rooms alongside versatile event spaces, plus amenities like a pool, spa, and fitness center housed in a historic former YMCA. Dining options include Idol Wolf’s inventive tapas and Good Press café, both ideal for casual client meetings or team gatherings.

Best for

  • Art-inspired client dinners & receptions
  • Executive offsites with unique cultural flair
  • Multi-night group stays near downtown attractions

Request a Package

Tell the venue what you're planning and they'll respond with a custom proposal within 1–2 business days.

Group Meeting

Custom request

Professional meeting space for your team — whether it's a meeting, training, workshop, or multi-day offsite. Half-day, full-day, or multi-day — with the option to request AV, catering, and your preferred room layout.

What's typically included

  • Meeting room & layout
  • Food & beverage
  • AV & technology

Room Block

Custom request

Reserve a block of rooms for your group — ideal for multi-day conferences, offsites, or any event where attendees are traveling from out of town.

What's typically included

  • Reserved guest rooms for your group
  • Flexible check-in & check-out dates
  • Negotiated group rates

Meeting + Room Block

Custom request

Bundle your meeting space and guest rooms in one request — perfect for multi-day offsites and conferences where the team meets by day and stays overnight.

What's typically included

  • Meeting room & layout
  • Food & beverage
  • AV & technology
  • Reserved guest rooms for your group

Venue Details

Standout features

Contemporary art gallery and installations throughout the hotel
Art Integration
Contemporary art gallery and installations throughout the hotel
The hotel doubles as a museum with a second-floor art gallery and immersive installations like The Way Out West stairwell piece, creating a culturally rich environment that guests can explore alongside their stay.
Idol Wolf’s playful Iberian-inspired tapas
Food & Beverage
Idol Wolf’s playful Iberian-inspired tapas
Idol Wolf offers a distinctive dining experience blending Spanish classics with Midwestern ingredients, perfect for shared business meals or casual gatherings in a stylish setting.
Locust Street Athletic and Swim Club in a restored YMCA building
Historic Fitness & Wellness
Locust Street Athletic and Swim Club in a restored YMCA building
The on-site fitness and spa facilities honor the building’s historic roots while providing modern wellness amenities including a unique pool and sauna, ideal for guest relaxation and event wellness breaks.

At a glance

Rated 4.1 on Google · 929 reviews